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Major IT outage - update

The Christie suffered an IT outage on Wednesday 27 March which affected most clinical services areas and means our clinicians have been unable to access some patient records and test results. This has also affected our network systems. It has been confirmed that this is not a cyber-attack.

The Christie Hotline (0161 446 3658) and switchboard (0161 446 3000) are working so patients can contact us as normal in this way.

We are working with our software provider engineers and systems should be resolved overnight, however this outage has caused delays in seeing and treating patients and some deferrals and cancellations. Our priority is providing safe care to all our patients and we apologise for any delays that may occur as a result of this incident.

Patients are reminded when they attend for their appointment to bring with them information about the treatment they are on, past medical history and medications which will help our staff if any systems are still intermittent on Thursday 28 March.

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Other publications - Sarah O'Dwyer

Effects of in vivo endotoxininfusions on in vitro cellular immune responses in humans
Rodrick ML, Moss NM, Grbic JT, Revhaug A, O'Dwyer ST, Michie HR, Gough DB, Dubravec D, Manson JM, Saporoschetz IB, et al
J Clin Immunol. 1992 Nov;12(6):440-50. PubMed PMID: 1287036 IF 2.654

Lower limb ischaemia and reperfusion alters gut permeability
Corson RJ, Paterson I, O'Dwyer ST, Kirkman E, Little R, McCollum CN
European J Vasc Surg 1992; 6: 158-163 IF 3.070

Tissue specific regulation of glutamine metabolism in muscle and intestine
O'Dwyer ST, Smith RJ, Rombeau JL, Wilmore DW
Am J Clin Nutr 1991; 2: 241-247 IF 6.918

Both cyclooxygenase-dependent and cyclooxygenase-independent pathways mediate the neuroendocrine response in humans
Michie H, Manogue K, O'Dwyer ST, Revhalig A, Wilmore DW
Surgery 1990; 108: 245-251 IF 3.105

Maintenance of small bowel mucosa with glutamine enriched parenteral nutrition
O'Dwyer ST, Smith RJ, Hwang TL, Wilmore DW
JPEN 1989; 13: 579-585 IF 3.143

Tumour necrosis factor and endotoxin induce similar metabolic effects in humans
Michie H, Spriggs DR, Manogue K, Revhaug A, O'Dwyer ST, Dinarello CA, Cerami Wolff SM, Wilmore DW
Surgery 1988; 104: 280-286 IF 3.105

Detection of circulating tumour necrosis factor during endotoxaemia in humans
Michie H, Manogue K, Spriggs DR, Revhaug A, O'Dwyer ST, Smith RJ, Wilmore DW
N Eng J Med 1988; 318: 1481-1486 IF 54.420

Combined effects of glutamine and epidermal growth factor on the rat intestine
Jacobs DO, Mealy K, Evans DA, O'Dwyer ST, Smith RJ, Wilmore DW
Surgery 1988; 104: 358-364 IF 3.105

Increased intestinal permeability associated with infection in burn patients
Zeigler TR, Smith RJ, O'Dwyer ST, Demling RH, Wilmore DW
Arch Surg 1988; 123: 1313-1319 IF 4.297

The gut - a central organ in surgical stress
Wilmore DW, Smith RJ, O'Dwyer ST, Jacobs DO, Zeigler TR, Wang X-D
Surgery 1988; 104: 917-923 IF 3.105

A single dose of endotoxin increases intestinal permeability in healthy humans
O'Dwyer ST, Michie H, Zeigler TR, Revhaug A, Smith RJ, Wilmore DW
Arch Surg 1988; 123: 1459-1464 IF 4.297

Last updated: January 2023