Clinical trials in rare lymphomas

Trial name

Description

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GEN3013

Phase 1/2 study using antibody GEN3013 to target CD20- expressing cells in patients with B cell non Hodgkin lymphoma

Suitable for patients with mantle cell, marginal zone and other B cell Non Hodgkin lymphomas

ENRICH

A phase 2/3 trial looking at treatment options for people over 60 with mantle cell lymphoma who are unable to have a stem cell transplant

Suitable for patients with mantle cell lymphoma who haven’t yet received any treatment

JCAR017

Phase 2 study determining efficacy and safety of JCAR017.

Suitable for patients with PCNSL, CNS involved lymphoma, Richter's transformation, and DLBCL which has come back after previous treatment

RIVA

A phase 2 trial testing the combination of rituximab and varlilumab.

Suitable for patients with various rare lymphoma types which have come back after previous treatment

MAGNOLIA

Phase 2 trial to test the safety and effectiveness of zanubrutinib also known as BGB-3111 in patients with marginal zone (MALT) lymphoma.

Suitable for patients with marginal zone lymphoma which has come back after previous treatment

GO29781

A phase 1/1b trial testing mosunetuzumab, on its own or with atezolizumab.

Suitable for patients with lymphoma which has come back after previous treatment