Clinical trials in rare lymphomas

Trial name

Description

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GEN3013

Phase 1/2 study using antibody GEN3013 to target CD20- expressing cells in patients with B cell non Hodgkin lymphoma

Suitable for patients with mantle cell, marginal zone and other B cell Non Hodgkin lymphomas

BI 1206 CRUK CD32b

Phase 1/2a study looking at blocking the CD32b protein with the antibody BI 1206.

Suitable for patients with various rare lymphoma types which have come back after previous treatment

ENRICH

A phase 2/3 trial looking at treatment options for people over 60 with mantle cell lymphoma who are unable to have a stem cell transplant

Suitable for patients with mantle cell lymphoma who haven’t yet received any treatment

JCAR017

Phase 2 study determining efficacy and safety of JCAR017.

Suitable for patients with PCNSL, CNS involved lymphoma, Richter's transformation, and DLBCL which has come back after previous treatment

RIVA

A phase 2 trial testing the combination of rituximab and varlilumab.

Suitable for patients with various rare lymphoma types which have come back after previous treatment

MAGNOLIA

Phase 2 trial to test the safety and effectiveness of zanubrutinib also known as BGB-3111 in patients with marginal zone (MALT) lymphoma.

Suitable for patients with marginal zone lymphoma which has come back after previous treatment

MCL Biobank

Non medicinal (observational) study suitable for patients with a recent diagnosis of mantle cell lymphoma.