Research news

New drug shrinks tumours in six advanced and hard-to-treat cancers

Results from a global clinical trial show that using a brand-new drug – currently called GRWD5769 – with an existing type of immunotherapy called cemiplimab can shrink tumours or keep them stable in people with six different advanced and hard-to-treat cancers.

Christie patient thankful for ground-breaking new brain tumour drug

47-year-old Jodie Goulborn from Merseyside has a type of brain tumour called a glioma. A ground-breaking new drug called vorasidenib has been keeping it at bay for over 4 years, and now that drug is available on the NHS. It’s the first time a new adult brain tumour treatment has been approved in 20 years.

Dad free from rectal cancer after taking part in clinical trial at The Christie

48-year-old Nick Cleworth, a train driver and dad-of-one from Swinton, is free from rectal cancer after taking part in a clinical trial at The Christie NHS Foundation Trust.

Major study launched to make advanced cancer treatments safer for patients

A major new UK study, led by The Christie NHS Foundation Trust and The University of Manchester, has been launched to help patients with cancer better tolerate cutting-edge immunotherapy treatments like CAR-T.

Research to support young brain tumour survivors

A research study conducted by The Christie NHS Foundation Trust in Manchester and The University of Manchester aims to improve the quality of life for young people who have survived a brain tumour.

Patient recruited to largest lung cancer clinical trial

David Mather, a retired company director from Hale in Greater Manchester is one of the first patients in the world to be recruited to the largest clinical trial using radiotherapy to treat lung cancer that has spread.

Christie researchers hope to ‘transform the landscape’ of children’s cancer treatment with groundbreaking radiotherapy project

Researchers at The Christie NHS Foundation Trust and The University of Manchester are hoping to identify how to reduce the long-term side effects radiotherapy can cause for children and young people.

New bladder cancer drug trialled at The Christie

A new experimental drug for the most common form of bladder cancer is showing promising results and could improve outcomes for patients in the future.

Stockport grandad free from blood cancer after being on a clinical trial at The Christie

A granddad from Stockport is showing no signs of cancer nearly 6 years after he first started on the FLAIR clinical trial at The Christie NHS Foundation Trust, a specialist cancer centre in Manchester.

Diabetes drug reduces side effects of hormone therapy in men with advanced prostate cancer

The STAMPEDE trial has recruited nearly 12,000 participants, making it the world's largest intervention prostate cancer trial.

Mum of 3 cancer-free after clinical trial at The Christie

A mother of 3 young children from Leigh in Greater Manchester is cancer-free thanks to a new drug being trialled at The Christie NHS Foundation Trust in Manchester.

Pre-operative immunotherapy increases the number of patients free from bowel cancer

An immunotherapy drug at The Christie in Manchester could help between 2,000 and 3,000 bowel cancer patients in the UK every year.

New breakthrough drug for leukaemia trialled at The Christie

A new drug being trialled at The Christie NHS Foundation Trust in Manchester could be a breakthrough for patients with a hard-to-treat form of leukaemia.

iMATCH funding

A group led by Professor Fiona Thistlethwaite, medical oncology consultant at The Christie has received funding from the National Institute for Health Research.

Wallasey woman defies the odds thanks to new drug trial

A woman from Merseyside with Non Hodgkin’s lymphoma is enjoying life thanks to trial drug capsules which have shrunk her tumours so they are too small to be measured.  

Christie researchers win prestigious social impact award

The Christie has won Bionow’s 2023 Social Impact Award for their redistribution of surplus clinical trial equipment from research teams in the trust to clinics in Africa.

Sheffield woman celebrates 6 years of successful experimental bowel cancer treatment

6 years on from her first treatment, Sara Anne Morley's tumours are stable after she was diagnosed with the most advanced kind due to treatment at The Christie.

The Christie pilots blood test to improve melanoma treatment

The Christie NHS Foundation Trust in Manchester has piloted a blood test in melanoma, the most serious form of skin cancer, to help determine which treatment to start with, and when to switch.

Woman struck twice with tonsil cancer sees tumours shrink by half on clinical trial

A woman with head and neck cancer has seen her tumours reduce by more than half thanks to a clinical trial at The Christie NHS Foundation Trust in Manchester.

Former football scout gets all clear after radiotherapy trial

A former football scout is cancer free and has avoided surgery for rectal cancer thanks to a clinical trial at The Christie NHS Foundation Trust in Manchester.

Lancashire man’s aggressive prostate cancer now close to undetectable thanks to a new drug trial at The Christie

A Lancashire man with aggressive prostate cancer has been told that his cancer is close to undetectable after just 4 months of being on a clinical trial at The Christie NHS Foundation Trust.

Secondary breast cancer patients may be spared routine scans thanks to Christie trial

Women with secondary breast cancer may be able to have their cancer monitored with a simple blood test, thanks to a trial at The Christie NHS Foundation Trust.

The Christie research to improve survival rates for lung cancer patients

The Christie in Manchester is running the world’s first research project to determine whether sparing the top of the heart during radiotherapy can help patients with lung cancer live longer.

Swinton cancer patient joins a clinical trial at The Christie at Oldham

A lung cancer patient from Swinton shares his story to encourage more patients to take part in radiotherapy clinical trials at The Christie at Oldham and other local treatment centres.

Trial drug helps rectal cancer patients avoid surgery

A Greater Manchester Police community support officer is cancer free thanks to a new drug being trialled at The Christie NHS Foundation Trust in Manchester.

Blood cancer trial gives former nurse new hope

A former cancer patient is now in complete remission thanks to a ground-breaking new myeloma clinical trial at The Christie NHS Foundation Trust in Manchester.

The Christie pioneers radiotherapy via the wrist

The Christie NHS Foundation Trust in Manchester is pioneering a procedure to treat liver cancer through the wrist to avoid overnight hospital stays.

Two trials reveal ‘hidden’ cancer for Christie patient

A man with a rare cancer with a poor prognosis is looking forward to a brighter future after taking part in 2 clinical trials at The Christie.

First experts move into new world-class cancer research facility at The Christie

World-leading scientists, clinicians and operational staff are moving into a new £150m cancer research centre at The Christie.

Christie patient injected with cancer-killing virus

A new type of cancer therapy is showing promising results in an early clinical trial for a patient who was previously given 6 months to live.

Christie lung cancer trial leads to game-changer drug available on NHS

A new drug called sotorasib which was trialled as a treatment for advanced non-small-cell lung cancer (NSCLC) at The Christie NHS Foundation Trust in Manchester is now available on the NHS.

Christie cancer trial improves outcome for men with hard-to-treat prostate cancer

Three specialists from The Christie given prestigious research award

3 prominent cancer researchers from The Christie NHS Foundation Trust have been given prestigious Senior Investigator status by NIHR.

Major funding for Manchester will help find new cancer treatments

Manchester Experimental Cancer Medicine Centre (ECMC) will receive a mayor funding investment of up to £3m for ancer research.

Clinical trial gives terminal cancer patient new lease of life

A retired school teacher has a new lease of life thanks to a new blood cancer drug she is taking on a clinical trial at The Christie in Manchester.

Christie clinical trial clears cancer for leukaemia patient

A patient at The Christie, who was diagnosed leukaemia, is now free of the disease thanks to an innovative treatment on a clinical trial.