What is Ewing Sarcoma?

Ewing Sarcoma is a rare type of cancer that attacks patients’ bones or the tissue around bones. It often begins in the soft tissue around the knee, although it can appear in any bone.

Ewing Sarcoma is most common among teenagers and people in their early 20s. It’s typical for people to see their doctor multiple times before they get a diagnosis, because the main symptom is usually ‘pain’. For somebody young who plays sport or leads an active life, it’s normal to attribute the pain to exercise.

Many patients are diagnosed with Ewing Sarcoma after months and sometimes even over a year of symptoms. Unfortunately, 25% of patients are diagnosed after the cancer has spread, which means it’s often harder to treat.

And for many young patients who have been treated for Ewing Sarcoma, the cancer can often come back. It’s just as hard to diagnose the second time – but a gift from you this Christmas could change that.

Why do Ewing Sarcoma patients need your help?

A Christmas donation from you could help to develop a blood test for the ‘combination gene’. This gene is a fusion between 2 genes caused by Ewing Sarcoma, where 2 chromosomes are stuck together in an abnormal way, producing a protein that drives tumour growth.

With your support, our scientists want to create a new blood test to spot this gene in patients with Ewing Sarcoma. This means our doctors can monitor patients receiving follow up for Ewing Sarcoma and discover recurrence quicker. Patients can then receive treatment much sooner – and they can get personalised treatment too.

Your support now could mean more young patients with Ewing Sarcoma could benefit from a blood test that you helped us develop. Give today using the form below.

Currently, recurrence of Ewing Sarcoma is only detected by a scan once it’s large enough. This means a standard biopsy test on the affected bone. This then goes to the pathologist and patients usually receive the results within a fortnight.

With the development of a new blood test to detect the combination gene, recurrence in patients could be found even when it is too small to be picked up on a scan. Patients could get their results much quicker, and tests will be less painful and invasive. In fact, the whole experience will be a lot less traumatic in every way.

This year, some young patients will have to spend their Christmas in the teenage and young adult service at The Christie, including those patients with Ewing Sarcoma. They’ll be looked after our clinical teams, including some of our fabulous nurses.

See why nurse Lyndsey is supporting our campaign to develop a new blood test for Ewing Sarcoma diagnosis. You can also read how nurse Suzy is making the festive season special for young patients and The Christie this Christmas.

With your donation, the new blood test will significantly help Ewing Sarcoma patients by identifying recurrence and showing us how effective treatment is. The quicker Ewing Sarcoma is detected, the more treatment options will be available, offering better patient outcomes and the chances of more Christmases to come.

But we can’t achieve this without you. Please help teenage and young adult patients with Ewing Sarcoma by making a Christmas gift today.