The Teenage and Young Adult oncology research team focuses on young people as individuals rather than defining them as cancer patients. We understand that these patients require expert treatment and support from the moment of diagnosis.

The wards and outpatient areas for TYA cancer patients have been developed by The Christie with additional charitable support, such as specialist nursing and youth support staff, funded by Teenage Cancer Trust and expert social work support provided by Clic Sargent. 

A National Council for Cancer Research Institute (NCRI) clinical studies development group (CSG) was created some years ago to address key areas of research for teenagers and young adults (aged 16 – 24) with cancer.  As well as being a member of the NCRI CSG, the lead clinician for TYA cancer research at The Christie, Dr Martin McCabe, chairs the National Cancer Intelligence Network (NCIN) Clinical Reference Group for TYA cancer patients and leads a national approach to data collection for young people

The focus of our work, and that of the Teenage Cancer Trust-funded academic programme in Manchester (£2.85M), is to define the types of tumours seen in this age group, to  optimise patient pathways and treatment and to optimise recruitment into clinical trials.

The team leads research projects in a wide range of aspects of cancer in children, teenagers and young adults. These include the genetic causes of childhood cancer, mechanisms underlying drug resistance, novel therapeutic approaches to cancer treatment, and psychosocial effects of treatment.

Our members are active in the national and international collaborative activity required to run clinical trials in these rare diseases. The team takes leading roles in the development and co-ordination of national and international trials such as rEECur (a European phase 2/3 trial for relapsed Ewing’s sarcoma).

Members of the group are active in both postgraduate and undergraduate teaching in the Institute of Cancer Sciences and Manchester Medical School.

Team objectives

  • To understand the genetic basis of cancer and its environmental causes
  • To improve our knowledge of treatment resistance
  • To develop novel therapeutic approaches to treatments
  • To improve service provision for these patients
  • To recruit more young patients to clinical trials including those who choose not to be treated at The Christie (Click here for more information) 
  • To increase knowledge of cancer in young people
  • To improve patient outcomes
  • To nurture medical students in the field of adolescent oncology

Team staff

  • Dr. M. McCabe, Paediatric Consultant Medical Oncologist
  • Sally Falk – Research Manager (Rare Tumour and Radiation Oncology Team)